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Index > Protein center > Tcf21(Gene name) > Mouse
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  • Tcf21 (Gene name),
  • Transcription factor 21 (Protein name ),  TCF21_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Tcf21(Pod1);
    Protein name:
    Transcription factor 21(TCF-21);
    Alternative:
    Epicardin;Capsulin;Podocyte-expressed 1(Pod-1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with TCF3 and binds the E box (5'-CANNTG-3').
    Function:
    Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. May be involved in the organogenesis of the spleen and heart and in cardiac and coronary artery development. May function in the development and sex differentiation of gonad via transcriptional regulation of AD4BP/SF-1.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    179
    Sequence:
    50:
    MSTGSLSDVE | DLQEVEMLDC | DSLKVDSNKE | FGTSNESTEE | GSNCENGSPQ | 
    100:
    KGRGGLGKRR | KAPTKKSPLS | GVSQEGKQVQ | RNAANARERA | RMRVLSKAFS | 
    150:
    RLKTTLPWVP | PDTKLSKLDT | LRLASSYIAH | LRQILANDKY | ENGYIHPVNL | 
    179:
    TWPFMVAGKP | ENDLKEVVTA | NRLCGTTAS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    UniGene:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse TCF-21
    Cat.:
    E12761h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse TCF-21
    Cat.:
    E12761b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse TCF-21
    Cat.:
    E12761m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse TCF-21
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse TCF-21
    Cat.:
    U12761h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse TCF-21
    Cat.:
    U12761m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse TCF-21
    Cat.:
    P12761Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse TCF-21
    Polyclonal Antibody for Mouse TCF-21
    Monoclonal Antibody for Mouse TCF-21
    Monoclonal Antibody for Mouse TCF-21
    Monoclonal Antibody for Mouse TCF-21
    Protein for Mouse TCF-21
    Protein for Mouse TCF-21
    Protein for Mouse TCF-21

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    References
    1. 1.
      "Cloning of capsulin, a basic helix-loop-helix factor expressed in progenitor cells of the pericardium and the coronary arteries."
      Hidai H. , Bardales R. , Goodwin R. , Quertermous T. , Quertermous E.E.
      Mech. Dev.73:33-43(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Embryo.
    2. 2.
      "Epicardin: a novel basic helix-loop-helix transcription factor gene expressed in epicardium, branchial arch myoblasts, and mesenchyme of developing lung, gut, kidney, and gonads."
      Robb L. , Mifsud L. , Hartley L. , Biben C. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Harvey R.P.
      Dev. Dyn.213:105-113(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BALB/c.
      tissue: Embryonic heart.
      tissue: Fibroblast.
      tissue: Uterus.
    3. 3.
      "Capsulin: a novel bHLH transcription factor expressed in epicardial progenitors and mesenchyme of visceral organs."
      Lu J.-R. , Richardson J.A. , Olson E.N.
      Mech. Dev.73:23-32(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Embryo.
    4. 4.
      "The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis."
      Quaggin S.E. , Schwartz L. , Cui S. , Igarashi P. , Deimling J. , Post M. , Rossant J.
      Development126:5771-5783(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: 129/Sv.
    5. 5.
      "Pod-1/Capsulin shows a sex- and stage-dependent expression pattern in the mouse gonad development and represses expression of Ad4BP/SF-1."
      Tamura M. , Kanno Y. , Chuma S. , Saito T. , Nakatsuji N.
      Mech. Dev.102:135-144(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    6. 6.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      strain: NOD.
      tissue: Embryo.
      tissue: Muellerian duct.
      tissue: Spleen.
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Colon.
    8. 8.
      "The basic helix-loop-helix transcription factor capsulin controls spleen organogenesis."
      Lu J.-R. , Chang P. , Richardson J.A. , Gan L. , Weiler H. , Olson E.N.
      Proc. Natl. Acad. Sci. U.S.A.97:9525-9530(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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